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💊 Cancer complex from multiple genetic disorders + cellular abnormalities
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- siRNAs can regulate gene expression following RNA interference (RNAi)
- post transcriptional mechanism that involves inhibition of gene expression through promoting cleavage on specific area of target mRNA
- shown promising therapeutics results for a good number of diseases especially in cancer → face drawbacks including stability and successful siRNA delivery in vivo [field of Nanomedicine as a whole is born out of this primary discovery]
- single targeted drugs for single targets fail to target the complex molecular pathways of cancer-causing agents → mixture of different therapies in immuno and chemo have been found to make targeted benefit vs individual therapeutic progress
- non-selective is bad→ goal to reduce recovery and time in hospitals → platform for development of novel, more effective diagnostic tools/less harmful treatments creates room for industrialization